Tretinoin gel is a powerful, prescription-strength topical retinoid (derived from vitamin A) primarily FDA-approved to treat acne vulgaris. By accelerating skin cell turnover and keeping pores clear, it prevents the formation of microcomedones (blackheads and whiteheads) and minimizes inflammatory acne breakouts. It is also widely used off-label to address fine facial wrinkles, sun damage, and hyperpigmentation (dark spots).